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In patients with JRA who are known or suspected to be poor CYP2C9 metabolizersconsider using alternative treatmentssee Use in Specific populationsand CLINICAL PHARMACOLOGY

Advise patients to report symptoms of ulcerations and bleedingincluding epigastric paindyspepsiamelenaand hematemesis to their health care providerIn the setting of concomitant use of low-dose aspirin for cardiac prophylaxisinform patients of the increased risk for and the signs and symptoms of GI bleedingsee WARNINGS AND PRECAUTIONS

In adult patients who are known or suspected to be healthy man viagra is it a scam. poor CYP2C9 metabolizers based on genotype or previous history/experience with other CYP2C9 substratessuch as warfarinphenytoininitiate treatment with half of the lowest recommended dose.

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