In healthy volunteers, plasma concentrations peak 6 to 24 hours median, about 17 hours after a single dose of lariam mefloquine .

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Mefloquine can pass into breast milk and may harm a nursing babyTell your doctor if you are breast-feeding a baby.

Lariammefloquineis indicated for the treatment of mild to moderate acute malaria caused by mefloquine-susceptible strains of Pfalciparumboth chloroquine-susceptible and resistant strainsor by Plasmodium vivaxThere are insufficient clinical data to document the effect of mefloquine in malaria caused by Povale or Pmalariae.

In several studiesthe administration of Lariammefloquinefor the treatment of malaria was associated with early vomiting in pediatric patientsEarly vomiting was cited in some reports as a possible cause of treatment failureIf a second dose is not toleratedthe patient should be monitored closely and alternative malaria treatment considered if improvement is not observed within a reasonable period of timesee DOSAGE AND ADMINISTRATION

If you have trouble swallowing the mefloquine tabletyou may crush the tablet and mix it into a small glass of milkwateror other beverage to make swallowing easier.

Lariam may cause serious mental problems in some peopleStop taking this medicine and contact your doctor immediately if you experience any of the following while taking Lariam:

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but lariam became increasingly controversial.