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Ayurveda describes two conditions known as mootrakruchra and mootraaghaatawhich coincide with the symptoms of prostatismMootrakruchra or strangury is characterized by severe pain in passing urine whereas in mootraaghaatathere is total suppression or intermittent flow of urine during urination.
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Naftopidil is an alpha 1Dselective blockerwhich has been recently reported to less likely induce ejaculatory disordersEfficacies on LUTS of the two alpha-1 blockerssilodosin and naftopidil are almost equivalentwith a small advantage of silodosin on voiding symptomsThe alpha 1Dselective blockernaftopidil may possess superior property of preserving sexual functionespecially for ejaculationcompared with the alpha 1Aselective blockersilodosin29]
Epristeridea novel 5 a-reductase inhibitoris an interesting drug in the treatment of BPHIt belongs to class of carboxy steroidIt has been shown to be an uncompetitive inhibitor against both testosterone and NADPHIts inhibitory action results from a preferential association to an enzyme binary complex containing NADP and henceincreases in testosterone concentration does not overcome its inhibitionIt is a specific inhibitor of type II 5 free trial viagra in canada. a-reductase isoenzymeIt also attenuates the growth rate of some androgen responsive prostate cancers34]
Combination therapy with doxazosin and finasteride has been shown to provide fast symptom reliefreduced prostate growthreduced risk of AURand the need for BPH-related surgery39]
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