Prednisone, a commonly used oral agent, may decrease inflammation by reversing increased capillary permeability and suppressing polymorphonuclear leukocyte pmn activity.

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Alternate day therapy is a corticosteroid dosing regimen in which twice the usual daily dose of corticoid is administered every other morningThe purpose of this mode of therapy is to provide the patient requiring long-term pharmacologic dose treatment with the beneficial effects of corticoids while minimizing certain undesirable effectsincluding pituitary-adrenal suppressionthe cushingoid statecorticoid withdrawal symptomsand growth suppression in children.

Taking NSAIDs with prednisone may increase your risk of stomach issues such as ulcers and bleedingExamples of NSAIDs include:

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs affect each person differentlywe cannot guarantee that this information includes all possible side effectsThis information is not a substitute for medical adviceAlways discuss possible side effects with a healthcare provider who knows your medical history.

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prednisolone is preferred to prednisone in significant hepatic disease because prednisolone does not require hepatic activation.